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Autoimmunity in acute ischemic stroke and the role of blood—brain barrier: the dark side or the light

Nikolay V. Tsygan, Alexandr P. Trashkov, Igor V. Litvinenko, Viktoriya A. Yakovleva, Alexandr V. Ryabtsev, Andrey G. Vasiliev, Leonid P. Churilov

Frontiers of Medicine 2019, Volume 13, Issue 4,   Pages 420-426 doi: 10.1007/s11684-019-0688-6

Abstract: This article presents a synopsis of the current data on the mechanisms of blood—brain barrier (BBB) alterationIschemic stroke is accompanied by aseptic inflammation, which alters the brain tissue and exposes theBBB disruption contributes to the leakage of brain autoantigens and induction of secondary autoimmuneImmune response is related to the key processes of blood clotting and fibrinolysis.At the same time, the stroke-induced immune activation may promote reparation phenomena in the brain.

Keywords： stroke     blood–brain barrier     autoimmunity     innate immunity     inflammation     cell death    

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Critical roles of chemokines and cytokines in antiviral innate immune responses during rabies virus infection

Ying HUANG, Clement Wesley GNANADURAI, Zhenfang FU

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3,   Pages 260-267 doi: 10.15302/J-FASE-2016116

Abstract: clearing RABV from the CNS is discussed, including recruiting leukocytes into the CNS, enhancement of bloodbrain barrier permeability and activation of various immune cells that are essential for viral clearance

Keywords： antiviral     blood brain barrier     chemokines and cytokines     innate immunity     rabies virus    

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Non-invasive continuous blood pressure monitoring: a review of current applications

Elena Chung, Guo Chen, Brenton Alexander, Maxime Cannesson

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 91-101 doi: 10.1007/s11684-013-0239-5

Abstract:

Blood pressure monitoring has come a long way from the initial observations made by Reverend HalesThere are none that deny the importance of monitoring perioperative blood pressure; however, the limitedblood pressure measurements leaves room for improvement.Invasive monitoring is able to detect beat-to-beat blood pressure measurement, but the risks inherent, and especially the creation of those offering non-invasive but continuous blood pressure monitoring

Keywords： non-invasive blood pressure monitoring     continuous blood pressure monitoring     invasive blood pressure monitoring    

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Relationship of endothelial nitric oxide synthase gene polymorphism with blood pressure, lipid profileand blood glucose level

TANG Zhongzhi, LI Junyao, YANG Jianhong

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 178-181 doi: 10.1007/s11684-008-0033-y

Abstract: To study the relationship of the polymorphism of endothelial nitric oxide synthase (eNOS) gene and bloodpressure, lipid profiles and blood glucose level.Taking into account eNOS Glu298Asp polymorphisms, the relationship of blood pressure with triglycerides(TG), total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL) and bloodThe distribution of eNOS Glu298Asp polymorphism had no significant difference between different blood
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Outcomes of patients awaiting lung transplantation after the implementation of donation after brain death

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 760-765 doi: 10.1007/s11684-021-0899-5

Abstract: outcomes of patients awaiting lung transplantation (LTx) after the implementation of donation after brain

Keywords： lung transplantation     donation after brain death     waitlist    

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White blood cell count and the incidence of hyperuricemia: insights from a community-based study

Jian Liu, Pingyan Shen, Xiaobo Ma, Xialian Yu, Liyan Ni, Xu Hao, Weiming Wang, Nan Chen

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 741-746 doi: 10.1007/s11684-017-0579-7

Abstract: The relationship between HUA and white blood cell (WBC) count remains unknown.

Keywords： white blood cell count     hyperuricemia     chronic kidney disease     inflammation    

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Cooling strategies and transport theories for brain hypothermia resuscitation

LIU Jing

Frontiers in Energy 2007, Volume 1, Issue 1,   Pages 32-57 doi: 10.1007/s11708-007-0004-z

Abstract: The brain is one of the most important organs in a biological body whose normal function depends heavilyproduction and consumption will occur which causes a rapid depletion of oxygen due to the interrupted blood-flowto the brain.Meanwhile, the cooling function of the blood flow on the hot tissue will be stopped, while metabolicallows a longer duration for the brain to endure reduced oxygen delivery.

Keywords： mathematical     interruption     hypothermia     metabolic     generation    

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Passive convergence-permeable reactive barrier (PC-PRB): An effective configuration to enhance hydraulic

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 12, doi: 10.1007/s11783-022-1591-y

Abstract:

● A novel PRB configuration based on passive convergent flow effect was proposed.

Keywords： Passive convergence-permeable reactive barrier (PC-PRB)     Permeable reactive barrier configuration     Numerical    

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Hydrogen production from methanol through dielectric barrier discharge

Baowei WANG, Xu ZHANG, Haiying BAI, Yijun Lü, Shuanghui HU

Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 2,   Pages 209-214 doi: 10.1007/s11705-010-1018-3

Abstract: In this paper, methanol reforming to produce H through dielectric-barrier discharge (DBD) plasma reaction

Keywords： methanol     dielectric-barrier discharge     hydrogen     plasma    

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gelatin-heparin nanofibrous scaffolds formed by a bi-layer electrospinning technique as potential artificial blood

Heyun WANG, Yakai FENG, Marc BEHL, Andreas LENDLEIN, Haiyang ZHAO, Ruofang XIAO, Jian LU, Li ZHANG, Jintang GUO

Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 3,   Pages 392-400 doi: 10.1007/s11705-011-1202-0

Abstract: In this paper, a scaffold, which mimics the morphology and mechanical properties of a native blood vesselbreaking strength (3.7±0.13 MPa) and an elongation at break (110±8%) that are appropriate for artificial bloodthe complex matrix structure of native arteries, and to have good biocompatibility as an artificial blood

Keywords： electrospinning     artificial blood vessels     scaffold     polyurethane     gelatin     nanofiber     hemocompatibility    

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Study of blood exposure-related mental health illness among clinical nurses

Xiaojia Xiong,Min Li,Yongliang Jiang,Xindeng Tong,Yanzhong Peng

Frontiers of Medicine 2017, Volume 11, Issue 1,   Pages 147-151 doi: 10.1007/s11684-016-0481-8

Abstract: This study aims to investigate the mental health status of nurses exposed to blood through needlestickNo significant difference between nurses exposed to blood and nurses not exposed to blood was found inResults from the GHQ-28 Standardized Questionnaire showed that 75.9% (123/162) of nurses exposed to bloodwere suspected to suffer from mental disorders, whereas 40% (56/140) of nurses not exposed to bloodThe mean mental health scores of nurses exposed to blood and those not exposed were 8.73±7.32

Keywords： blood exposure     needlestick injuries     mental health     nurses    

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Tramadol reinforces antidepressant effects of ketamine with increased levels of brain-derived neurotrophic

Chun Yang, Xiaomin Li, Nan Wang, Shixia Xu, Jianjun Yang, Zhiqiang Zhou

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 411-415 doi: 10.1007/s11684-012-0226-2

Abstract: Brain-derived neurotrophic factor (BDNF) is an important biomarker for mood disorders and tropomyosin-related

Keywords： tramadol     ketamine     antidepressant     brain-derived neurotrophic factor     tropomyosin-related kinase B    

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Endostatin specifically targets both tumor blood vessels and lymphatic vessels

Wei Zhuo, Yang Chen, Xiaomin Song, Yongzhang Luo

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 336-340 doi: 10.1007/s11684-011-0163-5

Abstract: Endostatin, a 20 kDa C-terminal fragment of collagen XVIII, was first identified as a potent angiogenic inhibitor. The anti-angiogenic function of endostatin has been well documented during the past decade. Recently, several studies demonstrated that endostatin also inhibits tumor lymphangiogenesis and lymphatic metastasis. However, the exact mechanism that endostatin executes its anti-angiogenic and anti-lymphangiogenic functions remains elusive. In the current mini-review, we briefly summarize recent novel findings, including the functions of endostatin targeting not only angiogenesis but also lymphangiogenesis, and the underlying mechanism by which endostatin internalization regulates its biological functions.

Keywords： endostatin     angiogenesis     lymphangiogenesis     nystatin     internalization     tumor    

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The influence of brain death on donor liver and the potential mechanisms of protective intervention

Shui-Jun ZHANG, Tao WANG

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 8-14 doi: 10.1007/s11684-011-0109-y

Abstract:

Brain-dead donors have become one of the main sources of organs for transplantation in Western countriesExperimental studies have confirmed the inferior graft survival of livers from brain-dead donors comparedStudies conducted in the past 10 years have shown that brain death is associated with effects on theHowever, whether the decrease in the viability of donor organs is caused by brain death or by the eventsbefore and after brain death remains uncertain.

Keywords： brain death     donor liver    

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Numerical modeling and performance evaluation of passive convergence-permeable reactive barrier (PC-PRB

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 11, doi: 10.1007/s11783-023-1731-z

Abstract:

● A 2D finite-element solute transport model, PRB-Trans, is developed.

Keywords： Passive convergence-permeable reactive barrier     Numerical modeling     Hydraulic behavior assessment     Pollutant    

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Title Author Date Type Operation

Autoimmunity in acute ischemic stroke and the role of blood—brain barrier: the dark side or the light

Nikolay V. Tsygan, Alexandr P. Trashkov, Igor V. Litvinenko, Viktoriya A. Yakovleva, Alexandr V. Ryabtsev, Andrey G. Vasiliev, Leonid P. Churilov

Journal Article

Critical roles of chemokines and cytokines in antiviral innate immune responses during rabies virus infection

Ying HUANG, Clement Wesley GNANADURAI, Zhenfang FU

Journal Article

Non-invasive continuous blood pressure monitoring: a review of current applications

Elena Chung, Guo Chen, Brenton Alexander, Maxime Cannesson

Journal Article

Relationship of endothelial nitric oxide synthase gene polymorphism with blood pressure, lipid profileand blood glucose level

TANG Zhongzhi, LI Junyao, YANG Jianhong

Journal Article

Outcomes of patients awaiting lung transplantation after the implementation of donation after brain death

Journal Article

White blood cell count and the incidence of hyperuricemia: insights from a community-based study

Jian Liu, Pingyan Shen, Xiaobo Ma, Xialian Yu, Liyan Ni, Xu Hao, Weiming Wang, Nan Chen

Journal Article

Cooling strategies and transport theories for brain hypothermia resuscitation

LIU Jing

Journal Article

Passive convergence-permeable reactive barrier (PC-PRB): An effective configuration to enhance hydraulic

Journal Article

Hydrogen production from methanol through dielectric barrier discharge

Baowei WANG, Xu ZHANG, Haiying BAI, Yijun Lü, Shuanghui HU

Journal Article

gelatin-heparin nanofibrous scaffolds formed by a bi-layer electrospinning technique as potential artificial blood

Heyun WANG, Yakai FENG, Marc BEHL, Andreas LENDLEIN, Haiyang ZHAO, Ruofang XIAO, Jian LU, Li ZHANG, Jintang GUO

Journal Article

Study of blood exposure-related mental health illness among clinical nurses

Xiaojia Xiong,Min Li,Yongliang Jiang,Xindeng Tong,Yanzhong Peng

Journal Article

Tramadol reinforces antidepressant effects of ketamine with increased levels of brain-derived neurotrophic

Chun Yang, Xiaomin Li, Nan Wang, Shixia Xu, Jianjun Yang, Zhiqiang Zhou

Journal Article

Endostatin specifically targets both tumor blood vessels and lymphatic vessels

Wei Zhuo, Yang Chen, Xiaomin Song, Yongzhang Luo

Journal Article

The influence of brain death on donor liver and the potential mechanisms of protective intervention

Shui-Jun ZHANG, Tao WANG

Journal Article

Numerical modeling and performance evaluation of passive convergence-permeable reactive barrier (PC-PRB

Journal Article